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. 2020 Jul 6;123(7):1114–1122. doi: 10.1038/s41416-020-0964-x

Fig. 1. Expression of p16INK4a in oropharyngeal squamous cell carcinomas (OPSCC) detected by immunostaining.

Fig. 1

a HPV–DNA-negative OPSCC without p16INK4a expression. b HPV16-DNA-positive OPSCC showing strong, diffuse overexpression of p16INK4a characteristic for HPV16-driven OPSCC. c HPV–DNA-negative OPSCC displaying p16INK4a overexpression similar to HPV16-driven OPSCC (b).