Figure 4.
Alluvial plots depicting the change from PI-RADS v2.0 assessments to v2.1 assessment for peripheral (left) and transition zone (right) lesions. Lesion biopsy status is encoded as follows: red: clinically significant (Gleason ≥ 3 + 4), orange non-significant (Gleason 3 + 3) and grey no cancer. Cancer frequencies in category 4 and 5 in PZ and in category 5 in TZ were high in both versions. Variation between the two scoring systems is seen especially in lower scores 1–3. In the PZ, 11 formerly category 2 lesions were upgraded to category 3 in PI-RADS v2.1. Among these only one GS ≥ 7 tumor was confirmed. In the TZ, 11 TZ lesions were downgraded from category 2 into category 1 in v2.1, all of which showed no tumor upon biopsy. 12 formerly category 2 lesions in the TZ were upgraded to category 3 in v2.1, one of them was a GS ≥ 7 cancer. V version, PZ peripheral zone, TZ transition zone, GS Gleason Score.