Table 3.
Diagnostic sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for detection of Gleason Score ≥ 7 tumor were calculated for PI-RADS version 2.0 and 2.1.
| PZ | TZ | |||||
|---|---|---|---|---|---|---|
| PI-RADS v2.0 (%) | PI-RADS v2.1 (%) | p value | PI-RADS v2.0 (%) | PI-RADS v2.1 (%) | p value | |
| Sensitivity | 95.4 | 94.3 | 1.00 | 95.8 | 93.8 | 1.00 |
| Specificity | 31.2 | 24.2 | 0.10 | 53.7 | 42.1 | 0.03* |
| PPV | 48.8 | 46.1 | 0.61 | 51.1 | 45.0 | 0.40 |
| NPV | 90.9 | 86.1 | 0.51 | 96.2 | 93.0 | 0.50 |
PI-RADS assessment categories were dichotomized using a predefined cut-off value: a PI-RADS category of ≥ 3 was defined as positive. Specificity in the TZ was significantly lower for PI-RADS version 2.1. All other diagnostic values did not differ significantly. *Results were declared to be significant if p < 5%.