Table 2.
Cortical regions showing significant effect in group analysis using 10 mm smooth kernals for CT and SA.
| Finding | Brain region | Size (mm2) | Talairach coordinates (x, y, z) | Cluster-wise P |
|---|---|---|---|---|
| Clusters survived CFT of p = 0.010 (Euler number not used as a covariate) | ||||
| LGI1: group-by-age | Left supramarginal cortex, extending to inferior parietal cortex | 970.67 | − 56.9, − 40.3, 38.2 | 0.0239 |
| LGI2: group-by-sex-by-age | Right inferior temporal cortex, extending to fusiform | 970.01 | 49.7, − 47.2, − 15.8 | 0.0190 |
| CT1: group | Right lateral orbitofrontal cortex, extending to frontal pole and medial orbitofrontal cortex | 558.99 | 14.7, 24.9, − 24.7 | 0.0056 |
| CT2: group-by-sex-by-age | Right lateral occipital cortex | 628.29 | 23.4, − 98.1, 1.9 | 0.0020 |
| Clusters survived CFT of p = 0.005 | ||||
| LGI2: group-by-sex-by-age | Right inferior temporal cortex, extending to fusiform | 793.15 | 49.7, − 47.2, − 15.8 | 0.0116 |
| CT2: group-by-sex-by-age | Right lateral occipital cortex | 503.96 | 23.4, − 98.1, 1.9 | 0.0012 |
| Additional clusters passed CFT of p = 0.050 (Euler number not used as covariate) | ||||
| LGI: group-by-sex-by-age | Left inferior temporal cortex, extending to fusiform, lateral occipital, lingual, and middle temporal cortices | 4448.51 | − 46.2, − 61.9, − 6.2 | 0.0002 |
| LGI: group-by-age | Right inferior parietal cortex, extending to supramarginal, superior parietal, and postcentral cortices | 2013.77 | 44.1, − 60.6, 45.5 | 0.0241 |
| SA: group-by-age | Right rostral middle frontal cortex, extending to superior frontal and frontal pole cortices | 2587.86 | 28.3, 41.4, 18.2 | 0.0016 |
| Clusters passed CFT of p = 0.050 (Euler number used as covariate) | ||||
| CT: group | Right lateral orbitofrontal cortex, extending to pars orbitals, pars triangularis, and insula cortices | 1177.73 | 16.2, 27.3, − 23.8 | 0.0056 |
| CT: group-by-age | Right superior parietal cortex, extending to inferior parietal, and precuneus cortices | 1109.23 | 21.8, − 62.7, 50.6 | 0.0064 |
| Euler effect: clusters survived CFT of p = 0.010 | ||||
| LGI | Left precentral cortex, extending to caudal middle frontal, postcentral, superior parietal, supramarginal cortices | 3899.52 | − 43.6, − 7.2, 45.8 | 0.0002 |
| LGI | Right inferior parietal cortex, extending to supramarginal, superior parietal, and superior temporal cortices | 3146.97 | 45.7, − 49, 11.5 | 0.0002 |
| LGI | Right rostral middle frontal cortex, extending to pars opercularis and pars triangularis | 858.76 | 43.7, 28.5, 22.4 | 0.0056 |
| SA | Right superior frontal cortex, extending to rostral middle frontal cortex | 1896.9 | − 7.6, 60.1, 20.4 | 0.0002 |