Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 1;31(17):1904–1916. doi: 10.1091/mbc.E19-11-0600

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Bilodeau et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License.

PMC Copyright notice

FIGURE 7: — Loss of PI4KIIIβ Increased the number of focal adhesions per cell. (A) The number of FA per cell is shown for WT cells (n = 60), a CRSPR-deleted line (n = 59), and a line rescued with WT-PI4KIIIβ (n = 60). The number of FA in the CRPSR line is significantly greater than in either the WT line of the one expressing WT PI4KIIIβ (respectively, p < 1 × 10^–5, p < 2 × 10^–7, t test). Bottom images show representative images of FA staining and image segmentation used to count FA for each line. (B) Blot showing that CRISPR cell lines have a defect in p-Y397 FAK phosphorylation in response to 400 mM sucrose. This defect is rescued by wt-PI4KB expression.