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. Author manuscript; available in PMC: 2020 Sep 30.
Published in final edited form as: Annu Rev Vis Sci. 2018 Jun 1;4:263–285. doi: 10.1146/annurev-vision-091517-034122

Figure 4. Development of ON-OFF segregation in ferret LGN.

Figure 4.

Top. Ferret LGN 2 days (P2), 10 days (P10) and 25 days (P25) after birth. Eye segregation is completed at P10 and ON-OFF segregation is completed at P25. A, C, C2: contralateral layers, A1, C1: ipsilateral layers. C3: layer not receiving retinal input, OT: optic tract, MIN: medial interlaminar nucleus, vLGN: ventral lateral geniculate nucleus, W: wing of the geniculate, on: on layers, off: off layers. Reproduced from (Speer et al 2010). Bottom. Cartoon illustrating the stages of retinal afferent segregation in LGN, first by eye and later by ON-OFF contrast polarity (based on (Speer et al 2010)).