Figure 1.
MSC pretreatment provides long‐term protection against the following pulmonary infection. (a) Scheme of the experiment. After receiving 5 × 105 MSCs or fibroblasts (FLS) or PBS (i.v.), mice were infected with 1 × 108 CFU Hi (i.n.). (b) Body weight changes were monitored. Uninfected mice were set as controls. n = 4 or 5 per group. (c, d) Mice were sacrificed on day 2 postinfection and bacteria in the BALF and lungs were determined. n = 4 per group. (e, f) Mice were treated with MSCs or PBS and then were infected with Hi at indicated time. Bacteria in the lungs were determined 2 days later. n = 4 per group. All the experiments were repeated at least three times. The representative data are shown.