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. 2020 Sep 25;15:7079–7096. doi: 10.2147/IJN.S250001

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© 2020 Badrigilan et al.

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(A) Morphological features of embryos injected with different concentrations of bismuth−asparagine coordination polymer spheres (BACP-2) at different times post-fertilization. (B) Alcian blue staining of BACP-2 effect on cartilage growth at 5 hours postfertilization (hpf) (a-j: lateral view; a’-l’: ventral view).(C) . Expression of krox20 (at 12 hpf), orthodenticle homeobox 2 (otx2) (at 12 hpf) and cardiac myosin light chain-2 (cmlc2) (at 24 hpf) genes in uninjected embryos and embryos after injection with 400 pg of BACP-2. Reprinted with permission from He N, Li X, Feng D, et al. Exploring the toxicity of a bismuth–asparagine coordination polymer on the early development of zebrafish embryos. Chem Res Toxicol. 2013;26(1):89–95.⁷³ Copyright 2013 American Chemical Society.