Table 2. Genotypes and allele frequencies of the INSR gene SNP, rs1799817, in patients with PCOS and the control group.
* significant (p<0.05). ** highly significant (p<0.001)
| Control 118 (%) | PCOS 126 (%) | OR | CI | 2-value | p-value | |
|---|---|---|---|---|---|---|
| Genotype Frequency | ||||||
| CC | 87 (73.7%) | 64 (50.7%) | Ref | |||
| CT | 21 (17.8%) | 47 (37.3%) | 2.82 | 1.6–5.0 | 12.50 | 0.0001 |
| TT | 10 (8.5%) | 15 (11.9%) | 2.03 | 0.86–4.8 | 2.66 | 0.1 |
| CT+TT | 31 (26.3%) | 62 (49.2%) | 2.59 | 1.53–4.37 | 12.92 | 0.0003** |
| Allele Frequency | ||||||
| C | 0.826 | 0.694 | Ref | |||
| T | 0.174 | 0.306 | 2.02 | 1.33–3.01 | 11.01 | 0.0009** |