Table 2.
Independent risk factors for ovarian metastasis
| Full model |
Conditional backward |
|||
|---|---|---|---|---|
| Characteristic | OR (95%CI) | p-value | OR (95%CI) | p-value |
| Age (years) | 0.93 | |||
| <40 | 1 | |||
| 40–49 | 1.16 (0.52–2.60) | 0.71 | ||
| ≥50 | 1.12 (0.55–2.30) | 0.76 | ||
| Histology type | <0.001 | <0.001 | ||
| SCC | 1 | 1 | ||
| Adeno | 4.68 (2.55–8.61) | <0.001 | 3.92 (2.29–6.72) | <0.001 |
| AS | 1.98 (0.75–5.21) | 0.17 | 1.54 (0.61–3.89) | 0.36 |
| Others | 1.42 (0.16–12.8) | 0.76 | 0.91 (0.11–7.50) | 0.93 |
| Tumor size | ||||
| ≤4 cm | 1 | |||
| > cm | 1.28 (0.71–2.31) | 0.42 | ||
| Parametria | ||||
| Not involved | 1 | |||
| Involved | 1.23 (0.66–2.30) | 0.52 | ||
| Deep stromal invasion | ||||
| No | 1 | |||
| Yes | 1.80 (0.62–5.21) | 0.28 | ||
| LVSI | ||||
| No | 1 | 1 | ||
| Yes | 2.34 (0.83–6.65) | 0.11 | 2.60 (1.09–6.19) | 0.031 |
| Uterine corpus | ||||
| Not involved | 1 | 1 | ||
| Involved | 6.21 (3.31–11.6) | <0.001 | 6.05 (3.56–10.3) | <0.001 |
| Pelvic lymph node | ||||
| Not involved | 1 | 1 | ||
| Involved | 3.19 (1.61–6.33) | 0.001 | 3.74 (2.02–6.95) | <0.001 |
| Para-aortic lymph node | <0.001 | <0.001 | ||
| Not involved | 1 | 1 | ||
| Involved | 4.75 (1.76–12.9) | 0.002 | 4.96 (2.02–12.2) | <0.001 |
| Clinically not involved | 0.94 (0.43–2.05) | 0.87 | 0.96 (0.47–1.96) | 0.90 |
| Peritoneal cytology | ||||
| No | 1 | |||
| Yes | 1.05 (0.58–1.89) | 0.88 | ||
| Hosmer and Lemeshow test | p = 0.44 | p = 0.80 | ||
Binary logistic regression models for multivariable analysis. In a full model, all the listed covariates were entered, and only statistically significant covariates in the final model were listed for a conditional backward model. Adjusted-odds ratio with 95% confidence interval are shown. Significant P-values (cutoff, p < 0.05) are emboldened.
Abbreviations: OR: odds ratio; CI: confidence interval; SCC: squamous cell carcinoma; Adeno: adenocarcinoma; AS: adenosquamous; LVSI: lymphovascular space invasion.