TABLE II.
Independent Risk Factors for Deep and Extensive Lymphovascular Space Invasion
| Deep LVSI |
Extensive LVSI |
|||
|---|---|---|---|---|
| OR (95%CI) |
P-value | OR (95%CI) |
P-value | |
| Age | 0.23 | 0.29 | ||
| <60 | 1 | 1 | ||
| ≥60 | 1.67 (0.72–3.86) |
0.50 (0.14–1.79) |
||
| Ethnicity | 0.73 | 0.023 | ||
| Non-hispanic | 1 | 1 | ||
| Hispanic | 0.86 (0.37–1.99) |
0.22 (0.06–0.81) |
||
| BMI (kg/m2) | 0.031 | 0.28 | ||
| <30 | 1 | 1 | ||
| ≥30 | 0.40 (0.18–0.92) |
0.49 (0.14–1.75) |
||
| Histology | 0.29 | 0.52 | ||
| Endometrioid | 1 | 1 | ||
| Non-endometrioid | 0.57 (0.20–1.64) |
1.59 (0.39–6.46) |
||
| Grade | <0.001 | 0.038 | ||
| 1–2 | 1 | 1 | ||
| 3 | 10.3 (4.03–26.6) |
4.51 (1.09–18.7) |
||
| Stage | 0.001 | 0.014 | ||
| I–II | 1 | 1 | ||
| III | 5.78 (1.97–16.9) |
6.42 (1.46–28.3) |
||
| Myometrial invasion (%) | <0.001 | <0.001 | ||
| ≤50% | 1 | 1 | ||
| >50% | 9.35 (3.93–22.2) |
17.6 (3.53–87.7) |
||
| Cervical stromal invasion | 0.92 | 0.75 | ||
| No | 1 | 1 | ||
| Yes | 1.06 (0.37–2.06) |
0.79 (0.18–3.40) |
||
| Adnexal involvement | 0.52 | 0.51 | ||
| No | 1 | 1 | ||
| Yes | 0.63 (0.16–2.55) |
0.55 (0.09–3.36) |
||
Multivariate analysis with binary logistic regression test for P-values. Covariates listed in table are entered in the final model. Significant P-values are in bold. BMI, body mass index; and LVSI, lymphovascular space invasion.