Table 2.

Association between HCQ and mortality

	Mortality odds ratio (95% CI)	p value
Model 1	0.44 (0.29–0.67)	< 0.001
Model 2	0.45 (0.30–0.68)	< 0.001
Model 3	0.39 (0.24–0.64)	< 0.001
Model 3 with a statistical interaction term for HCQ and azithromycin
1 Main effect HCQ	0.56(0.34–0.92)	0.022
2 Main effect azithromycin	0.53(0.19–1.50)	0.233
3 Interaction (1 and 2)	1.11(0.38–3.29)	0.846
Model 4	0.39 (0.24–0.64)	< 0.001

Model 1 Adjusted for age and gender

Model 2 Adjusted for age, gender, temperature > 37 °C, and saturation of oxygen < 90%

Model 3 Adjusted for age, gender, temperature > 37 °C, and saturation of oxygen < 90% treatment with azithromycin, steroids, heparin, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir

Model 4 Adjusted for age, gender, temperature > 37 °C, and saturation of oxygen < 90% treatment with azithromycin, steroids, heparin, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, and date of admission