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. 2020 Sep 29;20:253. doi: 10.1186/s12871-020-01139-y

Fig. 4.

Fig. 4

Sevoflurane partially reverses the reduction in cell survival by TRPV1 channel antagonism. Inhibition of Ca2+ influx through the TRPV1 receptor Ca2+ channel with the selective antagonist SB-366791 reduces cell survival in all three cell lines. Concomitant use of sevoflurane, but not propofol, partially reversed this effect. Data represents means ± SD from at least 9 repeats of 3 separate experiments and was analyzed by two-way ANOVA followed by Turkey multiple comparison tests. * P < 0.05, **** P < 0.0001