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. 2020 Sep 29;20:253. doi: 10.1186/s12871-020-01139-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Effects of general anesthetics (GAs) on breast cancer cell migration. a Representative images of the Transwell Migration Assay used to determine the invasiveness of estrogen receptor-positive (MCF 7) and negative breast cancer cell lines (MDA-MB-436). b MDA-MB-436 exhibits greater migration potential thanMCF7. Exposure to equipotent sevoflurane (2%) and propofol (2 μM) did not affect migration in either breast cancer cells. All data are expressed as means ± SD from at least repeats of 3 separate experiments in duplicate or triplicate wells, and analyzed by one-way ANOVA followed by Tukey multiple comparison tests