Table 2.
Comparison of the mean rank of symptoms and intensity of complaints assessed by the Premenstrual Symptoms Screening Tool (PSST) in the Echium amoenum and placebo groups before and during the first and second cycle of intervention
| PSST components | Placebo group n = 32 Mean rank |
Echium amoenum group n = 37 Mean rank |
**P-value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Base line | 1st cycle of intervention | 2st cycle of intervention | *P-value | Base line | 1st cycle of intervention | Second month | *P-value | ||
| Symptoms | |||||||||
| 1-Anger/irritability | 42.4 | 40.6 | 39.5 | 0.07 | 46.8 | 36.7 | 24.6 | < 0.001 | < 0.001 |
| 2-Anxiety/tension | 32.5 | 31.4 | 29.2 | 0.3 | 42.8 | 30.9 | 18.7 | < 0.001 | < 0.001 |
| 3-Tearful | 33.2 | 30.0 | 29.8 | 0.3 | 42.6 | 31.5 | 18.6 | < 0.001 | < 0.001 |
| 4-Depressed mood | 29.6 | 31.1 | 28.4 | 0.2 | 43.4 | 34.8 | 22.6 | < 0.001 | < 0.001 |
| 5-Decreased interest in work activities | 29.5 | 25.9 | 25.0 | 0.1 | 39.8 | 28.8 | 20.2 | < 0.001 | < 0.001 |
| 6-Decreased interest in home activities | 27.3 | 25.7 | 24.8 | 0.5 | 37.1 | 26.1 | 16.0 | < 0.001 | < 0.001 |
| 7-Decreased interest in social activities | 26.7 | 23.1 | 21.9 | 0.2 | 40.3 | 27.8 | 19.0 | < 0.001 | < 0.001 |
| 8-Difficulty concentrating | 36.4 | 34.3 | 32.8 | 0.1 | 34.7 | 30.4 | 22.3 | < 0.001 | 0.03 |
| 9-Fatigue/lack of energy | 37.7 | 35.4 | 32.9 | 0.1 | 43.2 | 31.8 | 20.2 | < 0.001 | < 0.001 |
| 10-Overeating/food cravings | 20.4 | 18.8 | 18.6 | 0.6 | 27.3 | 24.4 | 16.9 | < 0.001 | 0.005 |
| 11-Insomnia | 15.3 | 12.5 | 14.7 | 0.7 | 24.1 | 18.4 | 13.7 | 0.002 | 0.04 |
| 12-Hypersomnia | 31.1 | 29.1 | 26.9 | 0.1 | 35.4 | 21.4 | 17.9 | < 0.001 | < 0.001 |
| 13-Feeling overwhelmed | 31.2 | 30.1 | 27.6 | 0.2 | 40.0 | 26.9 | 18.3 | < 0.001 | < 0.001 |
| 14-Physical symptoms | 39.3 | 36.1 | 33.8 | 0.1 | 44.2 | 31.0 | 22.6 | < 0.001 | < 0.001 |
| Interference with | < 0.001 | ||||||||
| 15-work efficiency or productivity | 33.2 | 29.5 | 26.8 | 0.09 | 40.8 | 30.2 | 19.8 | < 0.001 | < 0.001 |
| 16-relationships with coworkers | 33.3 | 29.8 | 28.2 | 0.2 | 40.0 | 29.7 | 19.0 | < 0.001 | < 0.001 |
| 17-relationships with family | 34.9 | 31.8 | 31.0 | 0.1 | 36.0 | 27.7 | 22.1 | < 0.001 | 0.02 |
| 18-social life activities | 28.8 | 25.1 | 26.1 | 0.2 | 37.2 | 29.6 | 25.4 | < 0.001 | 0.02 |
| 19-home responsibilities | 25.2 | 23.7 | 23.2 | 0.3 | 35.9 | 24.4 | 20.8 | < 0.001 | 0.003 |
| Total | 31.0 | 29.4 | 28.3 | 0.09 | 35.3 | 24.2 | 16.1 | < 0.001 | < 0.001 |
*Within group P-value using Friedman test
**Between groups P-value using Mann-Withney test to compare the differences (baseline score-2nd follow up score) between two study groups
P-value < 0.05 considered statistically significant