Table 2.
Immune monitoring panel of pneumonia and stable kidney transplant recipients
| Parameters | All (n = 146) | Pneumonia (n = 46) | Stable (n = 100) | P value |
|---|---|---|---|---|
| Monocyte HLA-DR, MFI ± SD | 1247.17 ± 764.82 | 931.17 ± 671.15 | 1392.53 ± 764.37 | < 0.001 |
| Neutrophil CD64, MFI ± SD | 254.89 ± 409.29 | 589.20 ± 605.44 | 101.11 ± 54.08 | < 0.001 |
| CD3+ T cells/TBNK, mean ± SD (%) | 74.44 ± 10.83 | 76.79 ± 11.71 | 73.35 ± 10.28 | 0.015 |
| CD3+ T cells, n ± SD (cells/μl) | 1024.10 ± 596.64 | 628.51 ± 365.86 | 1206.07 ± 595.30 | < 0.001 |
| CD8+ T cells/TBNK, mean ± SD (%) | 36.56 ± 10.70 | 36.34 ± 9.97 | 36.66 ± 11.06 | 0.903 |
| CD8+ T cells, n ± SD (cells/μl) | 506.37 ± 343.93 | 294.23 ± 173.57 | 603.95 ± 359.21 | < 0.001 |
| CD4+ T cells/TBNK, mean ± SD (%) | 37.03 ± 10.46 | 39.65 ± 12.98 | 35.82 ± 8.90 | 0.127 |
| CD4+ T cells, n ± SD (cells/μl) | 506.35 ± 295.64 | 335.48 ± 221.42 | 584.96 ± 293.13 | < 0.001 |
| NK cells/TBNK, mean ± SD (%) | 15.74 ± 9.60 | 12.78 ± 8.81 | 17.11 ± 9.68 | 0.003 |
| NK cells, n ± SD (cells/μl) | 218.43 ± 179.47 | 107.39 ± 96.47 | 269.50 ± 185.96 | < 0.001 |
| B cells/TBNK, mean ± SD (%) | 8.80 ± 5.10 | 9.41 ± 6.84 | 8.52 ± 4.07 | 0.601 |
| B cells, n ± SD (cells/μl) | 117.27 ± 92.39 | 67.36 ± 45.47 | 140.23 ± 99.36 | < 0.001 |
| TBNK, n ± SD (cells/μl) | 1371.39 ± 751.49 | 809.90 ± 443.86 | 1629.67 ± 723.69 | < 0.001 |
| CD4/CD8 ratio, mean ± SD | 1.15 ± 0.60 | 1.21 ± 0.61 | 1.12 ± 0.59 | 0.320 |
Tested by Mann–Whitney U test
HLA-DR human leukocyte antigen-DR, MFI median fluorescence intensity, SD standard deviation, TBNK T, B and NK cells, NK cells natural killer cells