Table 3.
Multivariate linear regression analyses for serum soluble EGFR levels in T2DM patients
| Model 1 | Model 2 | |||||
|---|---|---|---|---|---|---|
| n | β | P | n | β | P | |
| Serum adipsin (μg/mL) | 106 | 0.100 | 0.273 | |||
| BMI | 106 | 0.070 | 0.502 | |||
| Waist circumference (cm) | 71 | 0.072 | 0.551 | |||
| Systolic blood pressure (mmHg) | 102 | − 0.105 | 0.247 | |||
| Diastolic blood pressure (mmHg) | 102 | − 0.010 | 0.918 | |||
| Fasting blood glucose (mg/dL) | 106 | 0.281 | 0.002 | 106 | 0.221 | 0.010 |
| Fasting serum insulin (μIU/mL) | 83 | 0.133 | 0.203 | |||
| C-peptide (ng/mL) | 100 | 0.129 | 0.181 | |||
| HOMA-IR | 83 | 0.224 | 0.030 | 83 | 0.193 | 0.035 |
| CPR-index | 100 | − 0.015 | 0.873 | |||
| HbA1c (%, mmol/mol) | 106 | 0.342 | < 0.001 | 106 | 0.240 | 0.007 |
| Total cholesterol (mg/dL) | 102 | 0.314 | < 0.001 | – | – | – |
| LDL-cholesterol (mg/dL) | 105 | 0.145 | 0.114 | |||
| HDL-cholesterol (mg/dL) | 106 | 0.189 | 0.047 | 106 | 0.182 | 0.044 |
| Triglycerides (mg/dL) | 106 | 0.198 | 0.041 | 106 | 0.014 | 0.894 |
| AST (IU/L) | 106 | 0.089 | 0.337 | |||
| ALT (IU/L) | 106 | 0.020 | 0.836 | |||
| γGTP (IU/L) | 105 | 0.173 | 0.064 | |||
| FIB4-index | 95 | 0.199 | 0.042 | 95 | 0.222 | 0.017 |
| eGFR (mL/min/1.73 m2) | 106 | − 0.024 | 0.804 | |||
Model 1: Adjusted for age and sex
Model 2: Adjusted for age, sex, and total cholesterol levels
BMI, Body mass index; EGFR, Epidermal growth factor receptor; eGFR, Estimated glomerular filtration rate; T2DM, Type 2 diabetes