Table 5.
Multivariate linear regression analyses for serum adipsin levels in T2DM patients
| Model 1 | Model 2 | |||||
|---|---|---|---|---|---|---|
| n | β | P | n | β | P | |
| Serum soluble EGFR (ng/mL) | 106 | 0.117 | 0.273 | |||
| BMI | 106 | 0.541 | < 0.001 | 106 | 0.470 | < 0.001 |
| Waist circumference (cm) | 71 | 0.523 | < 0.001 | 71 | 0.451 | < 0.001 |
| Systolic blood pressure (mmHg) | 102 | 0.045 | 0.653 | |||
| Diastolic blood pressure (mmHg) | 102 | 0.060 | 0.565 | |||
| Fasting blood glucose (mg/dL) | 106 | − 0.106 | 0.280 | |||
| Fasting serum insulin (μIU/mL) | 83 | 0.381 | < 0.001 | 83 | 0.345 | 0.001 |
| C-peptide (ng/mL) | 100 | 0.187 | 0.076 | |||
| HOMA-IR | 83 | 0.312 | 0.006 | 83 | 0.281 | 0.009 |
| CPR-index | 100 | 0.224 | 0.031 | 100 | 0.199 | 0.045 |
| HbA1c (%, mmol/mol) | 106 | 0.044 | 0.659 | |||
| Total cholesterol (mg/dL) | 102 | 0.001 | 0.992 | |||
| LDL-cholesterol (mg/dL) | 105 | − 0.133 | 0.178 | |||
| HDL-cholesterol (mg/dL) | 106 | − 0.035 | 0.736 | |||
| Triglycerides (mg/dL) | 106 | − 0.019 | 0.859 | |||
| AST (IU/L) | 106 | 0.112 | 0.261 | |||
| ALT (IU/L) | 106 | 0.106 | 0.308 | |||
| γGTP (IU/L) | 105 | 0.133 | 0.188 | |||
| FIB4-index | 95 | 0.214 | 0.045 | 95 | 0.277 | 0.007 |
| eGFR (mL/min/1.73 m2) | 106 | − 0.380 | < 0.001 | – | – | – |
Model 1: Adjusted for age and sex
Model 2: Adjusted for age, sex, and eGFR levels
BMI, Body mass index; EGFR, Epidermal growth factor receptor; eGFR, Estimated glomerular filtration rate; T2DM, Type 2 diabetes