Table 6.
Rates of other renal manifestations at baseline in overall population and by mutational status.
| Overall N = 2,211 | Patients with TSC1 mutationN = 196 | Patients with TSC2 mutation N = 654 | |
|---|---|---|---|
| Renal manifestations in patients with angiomyolipomas | |||
| Multiple renal cysts | 544 (24.6) | 26 (13.3) | 220 (33.6) |
| Polycystic kidneys | Not applicable* | 0 | 31 (4.7) |
| Renal malignancy | 31 (1.4) | 4 (2.0) | 8 (1.2) |
| Renal manifestations in patients without angiomyolipoma | |||
| Impaired renal function | 43 (1.9) | 6 (3.1) | 18 (2.8) |
CI, confidence interval; mTOR, mammalian target of rapamycin; N/A, not applicable; TSC, tuberous sclerosis complex.
Values are expressed as n (%).
PKD was observed only in those with TSC2 mutations.