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. 2020 Sep 16;11:972. doi: 10.3389/fneur.2020.00972

Table 6.

Rates of other renal manifestations at baseline in overall population and by mutational status.

Overall N = 2,211 Patients with TSC1 mutationN = 196 Patients with TSC2 mutation N = 654
Renal manifestations in patients with angiomyolipomas
  Multiple renal cysts 544 (24.6) 26 (13.3) 220 (33.6)
  Polycystic kidneys Not applicable* 0 31 (4.7)
  Renal malignancy 31 (1.4) 4 (2.0) 8 (1.2)
Renal manifestations in patients without angiomyolipoma
  Impaired renal function 43 (1.9) 6 (3.1) 18 (2.8)

CI, confidence interval; mTOR, mammalian target of rapamycin; N/A, not applicable; TSC, tuberous sclerosis complex.

Values are expressed as n (%).

*

PKD was observed only in those with TSC2 mutations.