Table 1.
Baseline characteristics of the study population by quintiles of TyG-index: Tehran Lipid and Glucose Study
| Variables | TyG-index quartiles | P-value | Total (n = 7521) | ||||
|---|---|---|---|---|---|---|---|
| 1 (< 8.4) | 2 (8.4–8.7) | 3 (8.7–9.0) | 4 (9.0–9.4) | 5 (≥ 9.4) | |||
| (n = 1503) | (n = 1506) | (n = 1504) | (n = 1504) | (n = 1504) | |||
| Age (years) | 43.1 ± 12.3 | 45.5 ± 12.2 | 47.1 ± 12.0 | 47.3 ± 11.7 | 50.3 ± 11.4 | < 0.001 | 46.6 ± 12.1 |
| Gender | |||||||
| Male | 588 (39.1) | 664 (44.1) | 696 (46.3) | 696 (46.3) | 723 (48.1) | < 0.001 | 3367 (44.8) |
| Female | 915 (60.9) | 842 (55.9) | 808 (53.7) | 808 (53.7) | 781 (51.9) | 4154 (55.2) | |
| WC (cm) | 83.2 ± 10.7 | 88.3 ± 10.9 | 91.7 ± 10.3 | 94.0 ± 10.6 | 96.5 ± 10.2 | < 0.001 | 90.7 ± 11.5 |
| BMI (kg/m2) | 25.1 ± 4.27 | 26.8 ± 4.39 | 27.9 ± 4.40 | 28.7 ± 4.32 | 29.1 ± 4.32 | < 0.001 | 27.5 ± 4.57 |
| Education (years) | |||||||
| < 6 | 451 (30.0) | 560 (37.2) | 604 (40.2) | 639 (42.5) | 789 (52.5) | < 0.001 | 3043 (40.5) |
| 6–12 | 834 (55.5) | 749 (49.7) | 708 (47.1) | 698 (46.4) | 559 (37.2) | 3548 (47.2) | |
| ≥ 12 | 218 (14.5) | 197 (13.1) | 192 (12.8) | 167 (11.1) | 156 (10.4) | 930 (12.4) | |
| Smoking | |||||||
| Never | 1164 (77.4) | 1118 (74.2) | 1134 (75.4) | 1118 (74.3) | 1101 (73.2) | 0.075 | 5635 (74.9) |
| Past | 104 (6.9) | 114 (7.6) | 122 (8.1) | 140 (9.3) | 142 (9.4) | 622 (8.3) | |
| Current | 235 (15.6) | 274 (18.2) | 248 (16.5) | 246 (16.4) | 261 (17.4) | 1264 (16.8) | |
| Low physical activity | 1002 (66.7) | 996 (66.1) | 1066 (70.9) | 1056 (70.2) | 1071 (71.2) | 0.002 | 5191 (69.0) |
| FH-CVD | 227 (15.1) | 239(15.9) | 239 (15.9) | 253 (16.8) | 264 (17.6) | 0.407 | 1222 (16.2) |
| T2D | 16 (1.1) | 54 (3.6) | 78 (5.2) | 195 (13.0) | 645 (42.9) | < 0.001 | 988 (13.1) |
| Hypertension | 162 (10.8) | 281 (18.7) | 375 (24.9) | 464 (30.9) | 577 (38.4) | < 0.001 | 1859 (24.7) |
| Lipid Lowering drugs | 6 (0.4) | 18 (1.2) | 41 (2.7) | 54 (3.6) | 154 (10.2) | < 0.001 | 273 (3.6) |
| LDL-C (mmol/L) | 2.98 ± 0.76 | 3.40 ± 0.81 | 3.61 ± 0.83 | 3.76 ± 0.92 | 3.91 ± 1.06 | < 0.001 | 3.53 ± 0.94 |
| HDL-C (mmol/L) | 1.23 ± 0.29 | 1.13 ± 0.29 | 1.05 ± 0.26 | 1.01 ± 0.24 | 0.95 ± 0.25 | < 0.001 | 1.07 ± 0.28 |
Data are represented as mean ± SD or frequency (percent)
TyG-index triglyceride and glucose index, WC waist circumference, BMI body mass index, FH-CVD family history of cardiovascular disease, T2D type 2 diabetes, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol