Table 4.

Clinical performance of the model to predict 10-year cardiovascular risk containing FRS and FRS + TyG-index models in the Population < 60 years (n = 6175): Tehran Lipid and Glucose Study

	FRS model* HR (95% CI)	P-value	FRS + TyG-index HR (95% CI)	P-value
Model components
FRS	1.07 (1.06–1.07)	< 0.001	1.06 (1.05–1.06)	< 0.001
TyG-index	–		1.42 (1.26–1.60)	< 0.001
Model predictive performance indexes
C-index	0.789 (0.773-0.805)	<0.001	0.771 (0.752–0.789)	< 0.001
IDI	–	–	0.001 (−0.004 to 0.007)	0.673

FRS Framingham risk score, TyG-index Triglyceride-Glucose index, HR hazard ratio, CI confidence interval, C-index Harrell’s concordance statistic, IDI integrated discrimination improvement

*FRS model: Framingham risk score model including age, gender, total cholesterol, high density lipoprotein cholesterol, systolic blood pressure, anti-hypertensive drugs, smoking, and type 2 diabetes