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. 2020 Sep 16;11:951. doi: 10.3389/fphys.2020.00951

TABLE 2.

Comparisons of anthropometric parameters between angiotensin-converting enzyme insertion/deletion subgroups of the pre- and post-menopause groups (M ± SD).

Characteristics Pre-menopause (n = 155)
Post-menopause (n = 236)
Pre vs. post (DD)
Pre vs. post (DI/II)
DD (n = 16) DI/II (n = 139) P DD (n = 30) DI/II (n = 206) P P P
Age (y) 42.88 ± 1.93 46.42 ± 3.61 0.000a 60.77 ± 6.61 61.88 ± 6.15 0.360
Height (cm) 160.81 ± 7.12 157.94 ± 6.18 0.053 158.02 ± 5.66 157.03 ± 6.06 0.390 0.293 0.801
Weight (Kg) 61.97 ± 7.98 61.67 ± 7.13 0.765 61.09 ± 7.50 59.74 ± 7.78 0.373 0.658 0.216
SBP (mm Hg) 132.09 ± 9.85 118.95 ± 9.02 0.009a 131.10 ± 10.91 129.68 ± 9.85 0.899 0.117 0.012d
DBP (mm Hg) 76.05 ± 7.86 68.37 ± 6.15 0.015b 77.43 ± 8.51 75.69 ± 9.38 0.436 0.300 0.006c

Independent-samples t-tests were used to compare continuous variables between pre- and post-menopause groups, and between ACE DI/II and ACE DD genotypes. SBP, systolic blood pressure; DBP, diastolic blood pressure; DD, homozygous deletion; DI/II, I allele carriers. Pre vs. Post (DD), comparison of pre- and post-menopausal women in DD group; Pre vs. Post (DI/II), comparison of pre- and post-menopausal women in I allele carriers. aSignificantly different between DD and II/ID groups, P < 0.01. bSignificantly different between DD and II/ID groups, P < 0.05. cSignificantly different between pre- and post-menopause groups, P < 0.01. dSignificantly different between pre- and post-menopause groups, P < 0.05.