TABLE 2.
Characteristics |
Pre-menopause (n = 155) |
Post-menopause (n = 236) |
Pre vs. post (DD) |
Pre vs. post (DI/II) |
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DD (n = 16) | DI/II (n = 139) | P | DD (n = 30) | DI/II (n = 206) | P | P | P | |
Age (y) | 42.88 ± 1.93 | 46.42 ± 3.61 | 0.000a | 60.77 ± 6.61 | 61.88 ± 6.15 | 0.360 | ||
Height (cm) | 160.81 ± 7.12 | 157.94 ± 6.18 | 0.053 | 158.02 ± 5.66 | 157.03 ± 6.06 | 0.390 | 0.293 | 0.801 |
Weight (Kg) | 61.97 ± 7.98 | 61.67 ± 7.13 | 0.765 | 61.09 ± 7.50 | 59.74 ± 7.78 | 0.373 | 0.658 | 0.216 |
SBP (mm Hg) | 132.09 ± 9.85 | 118.95 ± 9.02 | 0.009a | 131.10 ± 10.91 | 129.68 ± 9.85 | 0.899 | 0.117 | 0.012d |
DBP (mm Hg) | 76.05 ± 7.86 | 68.37 ± 6.15 | 0.015b | 77.43 ± 8.51 | 75.69 ± 9.38 | 0.436 | 0.300 | 0.006c |
Independent-samples t-tests were used to compare continuous variables between pre- and post-menopause groups, and between ACE DI/II and ACE DD genotypes. SBP, systolic blood pressure; DBP, diastolic blood pressure; DD, homozygous deletion; DI/II, I allele carriers. Pre vs. Post (DD), comparison of pre- and post-menopausal women in DD group; Pre vs. Post (DI/II), comparison of pre- and post-menopausal women in I allele carriers. aSignificantly different between DD and II/ID groups, P < 0.01. bSignificantly different between DD and II/ID groups, P < 0.05. cSignificantly different between pre- and post-menopause groups, P < 0.01. dSignificantly different between pre- and post-menopause groups, P < 0.05.