TABLE 5.
ERFs levels and comparisons (M ± SD).
| Genotype |
Pre-menopause (n = 155) |
Post-menopause (n = 236) |
Pre vs. Post (DD) |
Pre vs. Post (DI/II) |
||||
| DD (n = 16) | DI/II (n = 139) | P | DD (n = 30) | DI/II (n = 206) | P | P | P | |
| NO (μmol/l) | 61.239.78 | 66.1910.04 | 0.087 | 64.298.40 | 64.328.21 | 0.986 | 0.272 | 0.107 |
| ET-1 (ng/l) | 70.126.00 | 66.007.84 | 0.337 | 74.529.85 | 70.4610.21 | 0.202 | 0.379 | 0.014b |
| Ang II (pg/ml) | 135.5114.29 | 122.0712.89 | 0.029a | 126.8918.35 | 124.0017.99 | 0.540 | 0.202 | 0.463 |
Independent-samples t-tests were used to compare continuous variables between pre- and post-menopause groups, and between ACE DI/II and ACE DD genotypes. DD, homozygous deletion; DI/II, I allele carriers. NO, nitric oxide; ET-1, endothelin-1; Ang II, angiotensin II. Pre vs. Post (DD), comparison of pre- and post-menopausal women in DD group; Pre vs. Post (DI/II), comparison of pre- and post-menopausal women in I allele carriers. aSignificantly different between DD and DI/II groups, P < 0.05. bSignificantly different between pre- and post-menopause groups, P < 0.05.