Table 5.
Univariate analysis of prognostic factors for DFS in DM patients
| No. of patients | 3-y DFS rate | p | |
|---|---|---|---|
| Sex | |||
| Male | 58 | 82.6% | 0.716 |
| Female | 54 | 82.5% | |
| Age, y | |||
| <75 | 75 | 83.5% | 0.596 |
| ≥75 | 37 | 79.8% | |
| Preoperative CEA | |||
| <5 | 61 | 86.4% | 0.063 |
| ≥5 | 51 | 77.6% | |
| Postoperative CEA | |||
| <5 | 77 | 82.6% | 0.536 |
| ≥5 | 35 | 82.2% | |
| Tumor location | |||
| Right | 41 | 81.8% | 0.331 |
| Left | 37 | 72.8% | |
| Rectum | 34 | 93.9% | |
| Differentiation | |||
| Well | 8 | 70.0% | 0.414 |
| Moderately | 101 | 83.7% | |
| Poorly | 3 | 66.7% | |
| LVI | |||
| Yes | 56 | 78.3% | 0.467 |
| No | 56 | 86.5% | |
| PNI | |||
| Yes | 8 | 75.0% | 0.173 |
| No | 104 | 83.0% | |
| TNM stage | |||
| I | 35 | 93.7% | 0.029 |
| II | 44 | 79.1% | |
| III | 33 | 75.1% | |
| Smoking | |||
| Yes | 29 | 86.2% | 0.782 |
| No | 83 | 81.0% | |
| Metformin | |||
| Yes | 78 | 88.1% | 0.126 |
| No | 34 | 68.7% | |
CEA = carcinoembryonic antigen; DFS = disease-free survival; DM = diabetes mellitus; LVI = lymphovascular invasion; PNI = perineural invasion; TNM = tumor-node-metastasis.