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Disease-free survival (DFS) for patients with CNS3 randomly assigned to high-dose methotrexate with leucovorin rescue (HDMTX) with or without nelarabine; 5-year DFS rates were 93.1% ± 6.5% for HDMTX with nelarabine and 67.9% ± 12.2% for HDMTX without nelarabine (P = .014).
