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. 2020 Apr 21;29(9):1498–1519. doi: 10.1093/hmg/ddaa070

Figure 3.

Figure 3

Comparison of GTF2IRD1 and GTF2I binding sites. (A) GTF2I and GTF2IRD1 have different distributions of annotated binding sites. (B) GTF2IRD1-bound sequences are more conserved than GTF2I-bound sequences. (C) The overlap of genes that have GTF2I and GTF2IRD1 bound at their promoters. (D) Motifs of transcription factors that are enriched in regions bound by both GTF2I and GTF2IRD1. (E) GO analysis of genes with both GTF2I and GTF2IRD1 bound at their promoters. (F) Epigenome browser shot of Mapk14 showing peaks for both GTF2I and GTF2IRD1. (G) Enrichment of GTF2IRD1- and GTF2I-bound genes in ASD and conserved gene sets. *p < 0.05, **p < 0.01, ***p < 0.001.