TABLE 6.

MICs of tebipenem and comparators against strains used in microbiology studies^a

Strain	Compound and MIC (μg/ml)
In vitro	Tebipenem	Meropenem	Levofloxacin
E. coli ATCC 25922	0.015	0.03	0.015
E. coli ATCC 35218	0.015	0.015	0.03
K. pneumoniae ATCC 43816	0.03	0.03	0.03
K. pneumoniae ATCC 700603	0.06	0.03	0.5
Thigh study	Tebipenem	Levofloxacin	Ciprofloxacin
E. coli ATCC 25922	0.016	0.12	NA
UTI study	Tebipenem	Levofloxacin	Ciprofloxacin
E. coli ATCC 700928	0.016	0.03	NA
E. coli UTI89	0.016	NA	0.016
Lung study	Tebipenem	Meropenem	Tigecycline	Polymyxin B
K. pneumoniae ATCC 43816	0.06	0.03	0.5	NA
P. aeruginosa ATCC 27853	4	0.5	NA	1

^aUTI, urinary tract infection; NA, not applicable (not used as a comparator in the study).