FIG 5.

Survival analysis and cardiac parasite load in chronically T. cruzi-infected BALB/c mice. Mice were infected with T. cruzi trypomastigotes and treated with simvastatin on day 60 postinfection for 20 days. (A) Kaplan-Meier survival analysis from one experiment (n = 9). (B) Parasite load as determined by qPCR from the hearts of mice on day 80 postinfection. Results are expressed as the number of parasite equivalents per milliliter of heart homogenate. Data are expressed as the means ± standard errors from one experiment (n = 9). One-way ANOVA was performed to identify significant differences. *, P ≤ 0.05.