TABLE 1.
MICs for 20 Mycobacterium abscessus clinical strains and the reference strain ATCC 19977 of ceftaroline and imipenem with and without relebactam (REL) and avibactam (AVI)
| M. abscessus isolate | MIC (μg/ml) of: |
|||||
|---|---|---|---|---|---|---|
| Ceftaroline |
Imipenem |
|||||
| Alone | +REL (4 μg/ml) | +AVI (4 μg/ml) | Alone | +REL (4 μg/ml) | +AVI (4 μg/ml) | |
| UHCMC 1 | 8 | 4 | 1 | 1 | 1 | 1 |
| UHCMC 2 | 16 | 2 | 2 | 1 | 2 | 1 |
| UHCMC 3 | 16 | 4 | 0.5 | 2 | 2 | 0.5 |
| UHCMC 4 | 16 | 4 | 0.25 | 2 | 2 | 1 |
| UHCMC 5 | 8 | 2 | 0.5 | 1 | 1 | 1 |
| UHCMC 6 | 32 | 4 | 1 | 2 | 2 | 1 |
| UHCMC 7 | 8 | 4 | 0.5 | 1 | 1 | 1 |
| UHCMC 8 | 8 | 4 | 1 | 1 | 1 | 1 |
| UHCMC 9 | 4 | 2 | 0.5 | 0.5 | 1 | 1 |
| UHCMC 10 | 4 | 1 | 0.5 | 1 | 1 | 1 |
| Metro 1 | 4 | 2 | 1 | 1 | 1 | 1 |
| Metro 2 | 32 | 4 | 1 | 2 | 2 | 0.5 |
| Metro 3 | 4 | 2 | 0.25 | 1 | 2 | 1 |
| Metro 4 | 4 | 1 | 0.5 | 2 | 2 | 1 |
| Metro 5 | 16 | 2 | 1 | 1 | 1 | 1 |
| Metro 6 | 4 | 2 | 0.5 | 1 | 1 | 1 |
| Metro 7 | 4 | 1 | 1 | 2 | 2 | 0.5 |
| Metro xx2 | 8 | 4 | 0.5 | 1 | 1 | 1 |
| Metro xx3 | 16 | 8 | 1 | 1 | 2 | 1 |
| UHCMC RodI2 | 8 | 4 | 0.25 | 1 | 1 | 1 |
| ATCC 19977 | 16 | 4 | 1 | 1 | 1 | 1 |