TABLE 4.
Kinetic parameters of BlaMab hydrolysis of ceftaroline fosamil and imipenem
| Compound | kcat (s−1) | Km (μM) | kcat/Km (μM−1 s−1) |
|---|---|---|---|
| Imipenem | 0.95 ± 0.09 | 17 ± 2 | 0.056 ± 0.006 |
| Ceftaroline fosamil | 4.7 ± 0.5 | 682 ± 70 | 0.007 ± 0.001 |
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