TABLE 7. Recommended vaccination schedule and intervals for microbiologists routinely exposed to isolates of Neisseria meningitidis — Advisory Committee on Immunization Practices, United States, 2020.
Age group | Serogroups A, C, W, and Y meningococcal conjugate vaccines MenACWY-D (Menactra, Sanofi Pasteur)* or MenACWY-CRM (Menveo, GlaxoSmithKline)† or MenACWY-TT (MenQuadfi, Sanofi Pasteur)§ | Serogroup B meningococcal vaccines MenB-FHbp (Trumenba, Pfizer) or MenB-4C (Bexsero, GlaxoSmithKline) |
---|---|---|
≥10 yrs | Primary vaccination: MenACWY-D or MenACWY-CRM or MenACWY-TT: 1 dose Boosters (if person remains at increased risk)**: Single dose at 5 yrs after primary vaccination and every 5 yrs thereafter | Primary vaccination¶: MenB-FHbp: 3 doses at 0, 1–2, and 6 mos or MenB-4C: 2 doses ≥1 mo apart Boosters (if person remains at increased risk)††: Single dose at 1 yr after completion of primary vaccination and every 2–3 yrs thereafter Note: MenB-FHbp and MenB-4C are not interchangeable |
Abbreviations: MenACWY-CRM = meningococcal groups A, C, W, and Y oligosaccharide diphtheria CRM197 conjugate vaccine; MenACWY-D = meningococcal groups A, C, W, and Y polysaccharide diphtheria toxoid conjugate vaccine; MenACWY-TT = meningococcal groups A, C, W, and Y polysaccharide tetanus toxoid conjugate vaccine; MenB-4C = four-component meningococcal group B vaccine; MenB-FHbp = meningococcal group B factor H binding protein vaccine.
* Licensed in the United States only for persons aged 9 months–55 years. Vaccination of persons aged ≥56 years is considered off-label.
† Licensed in the United States only for persons aged 2 months–55 years. Vaccination of persons aged ≥56 years is considered off-label.
§ Licensed in the United States only for persons aged ≥2 years.
¶ Licensed in the United States only for persons aged 10–25 years. Vaccination of persons aged ≥26 years is considered off-label.
** Licensed in the United States only for a single booster dose for persons aged 15–55 years for MenACWY-D and MenACWY-CRM or aged ≥15 years for MenACWY-TT. Booster doses administered outside of these ages or administration of >1 booster dose are considered off-label.
†† Licensed in the United States only for a primary series. Administration of booster doses is considered off-label.