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Methamphetamine increases neuronal toxicity in HIV-treated human primary neurons. MAP2 antibody was used for staining neuronal dendrites. (A) Confocal laser microscopy showing a healthy MAP2 dendritic network (as indicated by the white arrows). (B to H) HIV, methamphetamine, and combination treatments induced dendritic beading and dendritic size reduction (as indicated by the white dashed arrows). Scale bar, 10 μm.
