FIG 2.

Characterization of the GPgV genome and polyprotein. (A) GPgV-1 genome and polyprotein organization. Putative cleavage sites within the polyprotein are indicated by a red rhombus (structural proteins) or an orange rhombus (nonstructural proteins). Sequence alignment shows a comparison of the predicted cleavage sites for cellular signalase and viral proteases in the GPgV-1 polyprotein with other pegiviruses. (B) Locations and sequence comparisons of the conserved NS2 protease motif, NS3 protease catalytic triad, zinc-binding residues, Walker A, Walker B, and NS5B RNA-dependent RNA polymerase motifs.