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. Author manuscript; available in PMC: 2020 Sep 30.
Published in final edited form as: Gene. 2012 Feb 22;499(1):1–7. doi: 10.1016/j.gene.2012.02.015

Table I.

Protein Phosphatases targeting pocket proteins

Signal Phosphatase Pocket Protein
(or smads)		 Reference
Inducible Signals
  H2O2/ Oxidative Stress PP2A/PR48/PR70 pRb Magenta et al., 2008
PP2A/? p107, p130 Cicchillitti et al., 2003
  UV Irradiation PP2A/PR59 p107 Voorhoeve et al., 1999b
  All-trans- Retinoic Acid PP2A/? p130 Purev et al., 2006
  FGF PP2A/B or B' p107 Dailey et al., 2003, Kolupaeva et al., 2008
  TGFβ PP2A/? p107 Chen et al., 2002
  BMP PP2A/B55β Smads Bengtsson et al., 2009
Cell Cycle
  Throughout PP2A/B55α p107, p130 Jayadeva et al., 2010
PP2A/PR70? pRb Jayadeva et al., 2010
  Mitosis/Early G1 PP1α2 pRb Ludlow et al., 1993, Durfee et al., 1993
PP2A + CDK inhibition pRb?, p107?, p130? Calbó et al., 2002, Garriga et al., 2004