Fig. 4.

Electrostatic (ΔE_ele + ${\mathrm{\Delta }G}_{\text{solv}}^{\text{ele}}$, red) and vdW (ΔE_vdW + ${\mathrm{\Delta }G}_{\text{solv}}^{\text{nonpolar}}$, black) energy contributions from each residue of SARS-CoV-2 nsp16 to the binding of SAH (top) and SFG (bottom) derived from MD1. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)