Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 30;10:16136. doi: 10.1038/s41598-020-73014-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Multivariate clustering analysis upon SEB stimulation in the validation cohort. 10 healthy volunteers and 30 septic patients were treated as a whole to discriminate associative gene patterns. SEB response revealed 3 clusters (SV1; n = 11, SV2; n = 14 and SV3; n = 15) using PAM method with correlation distance. The homemade dendogram is based on the distance between the individuals from the medoid of each cluster found by PAM. Darker purple colours on the heat map indicates higher fold change for upregulated genes (stimulation/control condition), while darker orange colours indicate higher fold change for downregulated genes. 10,000 AB/c was used as a threshold for high and low mHLA-DR. SEB staphylococcal enterotoxin B, HLA-DR human leukocyte antigen DR, HAI hospital-acquired infection.