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. 2020 Sep 17;11:570846. doi: 10.3389/fendo.2020.570846

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Copyright © 2020 Preston, Larsen, Eclov, Louwagie, Gandy, Faustino and Baack.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional pathways prioritized in differentially expressed genes from combination exposed group. Functional annotation and pathways analysis was done using Reactome pathway database in down and upregulated differentially expressed genes (DEGs) of combination exposed group when compared to control. (A) Analysis of the upregulated DEGs elicited four mitochondrial translation-related pathways, associated with Dap3, Mrpl38, Mrps10, Mrpl19, Mrps27, Mrpl40. (B) Downregulated list revealed nine functional pathways directly associated with fibroblast growth factor receptor 2 (Fgfr2).