Table 4. Correlation between GTF2IRD1 and immune-related terms based on ESTIMATE algorithm and ssGSEA.

Algorithm	Terms	TCGA		GSE62452		GSE79668		GSE60979
		Cor	P-value	Cor	P-value	Cor	P-value	Cor	P-value
ESTIMATE	Tumor purity	0.40	<0.0001	0.46	<0.0001	0.091	0.53	0.39	0.0052
	Immune score	−0.36	<0.0001	−0.51	<0.0001	−0.21	0.13	−0.44	0.0016
ssGSEA	CD8+ T cells	−0.41	<0.0001	−0.42	<0.001	−0.30	0.031	−0.41	0.0037
	TILs	−0.41	<0.0001	−0.51	<0.0001	−0.13	0.35	−0.45	0.0011
	Cytolytic activity	−0.42	<0.0001	−0.44	<0.001	−0.26	0.060	−0.34	0.017
	T-cell co-stimulation	−0.28	<0.0001	−0.48	<0.0001	−0.32	0.020	−0.44	0.0014

P-value < 0.05 was considered statistically significant.