TABLE 2.

Descriptions of brain regions for the main effect of diagnosis and the interaction effect of genotype and diagnosis on caudate FC.

Brain regions (AAL)	Peak MNI coordinates (mm)			Peak F value	Cluster size (mm3)
	X	Y	Z
Main effect of disease
Left inferior orbit frontal gyrus	−12	18	0	24.98	348
Right inferior orbit frontal gyrus	27	15	−12	25.85	244
Right superior occipital gyrus	24	−84	42	22.85	211
Disease × genotype interaction
Right middle occipital gyrus/Right middle temporal gyrus	42	−72	12	12.47	158

These findings correspond to a voxel-wise height threshold of P < 0.001 (uncorrected) combined with a cluster-level extent threshold of P < 0.05 (corrected for multiple comparisons using the FWE rate). AAL, automated anatomical labeling; MNI, Montreal Neurological Institute.