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Spatial reference memory was measured in a probe test. Animals fed with a HFD spent less time in the target zone (a). HFD animals treated with LY341495 spent more time in the target zone in compare with HFD animals. Animals in all groups showed no difference in escape latency (b) to find a visible platform. Data presented as means ± S.E.M. * p < 0.05, ** p < 0.01, ns; not significant.
