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. 2020 Sep 17;11:458. doi: 10.3389/fendo.2020.00458

Table 4.

Multiple pregnancy, miscarriage and birth defects rate of all kinds of ART in 2013–2016.

2013 2014 2015 2016 Total
MPR (%) MR (%) BDR (%) MPR (%) MR (%) BDR (%) MPR (%) MR (%) BDR (%) MPR (%) MR (%) BDR (%) MPR (%) MR (%) BDR (%)
IVF 34.2 14.7 0.9 33.8 14.4 0.8 33.4 14.1 0.9 33.0 15.0 0.9 33.6 14.5 0.9
ICSI 33.8 13.4 0.9 33.2 13.9 0.9 32.7 14.1 1.0 32.0 14.1 1.0 32.9 13.9 0.9
PGD/PGS 30.5 19.5 0.4 24.4 16.5 0.8 13.4 17.2 0.5 1.7 13.6 1.4 12.4 15.8 1.0
FET 32.3 16.0 0.8 31.8 16.4 0.8 31.6 16.0 0.7 29.4 16.8 0.9 31.0 16.4 0.8
DS 33.9 6.6 1.3 37.8 11.9 0.7 32.6 11.9 0.7 31.5 11.7 1.2 33.9 10.9 0.9
DE 42.6 13.5 0.6 28.0 14.0 0.7 33.7 12.2 0.5 31.6 11.3 1.4 33.8 12.8 1.1

DS, IVF/ICSI cycles using donor sperm; DE, IVF/ICSI cycles using donor egg.

MPR, multiple pregnancy rate, calculated using the number of multiple pregnancy cycles divided by the number of pregnancy.

MR, miscarriage rate, calculated using the number of miscarriage cycles divided by the number of pregnancy.

BDR, birth defects rate, calculated using the number of infants with birth defects divided by the total number of infants.