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A) Measured response of rat plasma PL AA (20:4n-6) as a function of dietary PUFA, LA and ALA in a fixed proportion of 9.4:1. The plasma AA rises to reach a plateau at 3–4%en (energy). B) Hypothetical response of the three rs66698963 Indel genotypes to increasing dietary PUFA. Three different plateau levels are achieved corresponding to C) the measured blood levels found in the Chinese cohort. Panel A redraw from Gibson, PLEFA 2013.
