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FADS2 catalyzes reactions of at least 16 substrates at three positions.
| Desaturation Position | Substrate |
|---|---|
| Δ4-desaturation |
22:5n-3→22:6n-3 22:4n-6→22:5n-6 |
| Δ6-desaturation |
18:3n-3→18:4n-3 18:2n-6→18:3n-6 18:1n-9→18:2n-9 24:5n-3→24:6n-3 24:4n-6→24:5n-6 16:0→16:1n-10 17:0→17:1n-11 iso16:0→iso6Z-16:1 iso18:0→iso6Z-18:1 iso17:0→iso6Z-17:1 anteiso17:0→anteiso6Z-17:1 |
| Δ8-desaturation |
20:1n-9→20:2n-9 20:3n-3→20:4n-3 20:2n-6→20:3n-6 |
