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. 2020 Sep 22;2020:8851525. doi: 10.1155/2020/8851525

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Copyright © 2020 Na Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cisplatin activates PVM/Ms in SV. (a) The distribution of PVM/Ms by immunofluorescence staining. PVM/Ms were marked with a special antibody against CD68 (red) and strial capillaries with Griffonia Simplicifolia IB4 (gray). Nuclei were stained with DAPI (blue). The PVM/Ms were highly invested on the abluminal surface of capillaries. Scale bars, 100 μm. (b) Zoom in of immunofluorescence staining. (c) Quantification of CD68-positive infiltration per SV area (n = 5). (d) qRT-PCR shows mRNA for IL-1β in the SV. n = 6. ^∗∗p < 0.01 and ^∗∗∗p < 0.001.