Table 1.

In vivo performance for ADx-001 contrast-enhanced MRI for identification of amyloid positive mice at different dose levels of ADx-001.

ADx-001 dose (mmol Gd/kg)	T1w-SE			FSE-IR
	Accuracy (%)	Sensitivity (%)	Specificity (%)	Accuracy (%)	Sensitivity (%)	Specificity (%)
0.20	91.7	83.3	100	91.7	83.3	100
0.15	58.3	16.7	100	83.3	66.7	100
0.10	75	50	100	58.3	16.7	100

Six mice were tested for both genotypes (Tg and WT) at all three dose levels (0.20, 0.15, and 0.10 mmol Gd/kg) for a total of 36 mice.