Table 1. Baseline characteristics of newly diagnosed GBM patients.
Patient characteristics | n = 90 |
---|---|
Age at diagnosis, yr (IQR) | 64 (55–70) |
Gender | |
Male (%) | 47 (52) |
Female (%) | 43 (48) |
Race | |
White (%) | 75 (97) |
Black (%) | 2 (3) |
Ethnicity | |
Hispanic (%) | 75 (97) |
Non-Hispanic (%) | 2 (3) |
IDH-1 status | |
WT (%) | 84 (93) |
Mutated (%) | 6 (7) |
MGMT promoter | |
Unmethylated (%) | 53 (59) |
Methylated (%) | 34 (38) |
P53 stain, % (IQR) | 5 (2–20%) |
Ki67, % (IQR) | 30 (16–40%) |
Preoperative steroid use, n (%) | 85 (94) |
Median overall survival, mo (95% confidence interval) | 15 (12–19) |
1-yr survival, n at risk (survival probability) | 37 (59%) |
2-yr survival, n at risk (survival probability) | 12 (26%) |
IDH, isocitrate dehydrogenase; IQR, interquartile range; MGMT, O[6]-methylguanine-DNA.