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. 2020 Sep 29;218(1):e20200030. doi: 10.1084/jem.20200030

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© 2020 Mishra et al.

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Figure S2. — T-bet deficiency does not impact GC reaction or CD8⁺ T reg cells. Representative FACS profiles of splenocytes isolated from 5-mo-old mice. Tgfbr2^−/− mice have been described in the main text; Tbx21^−/− mice are Tbx21^f/fdLck-cre mice; and Tgfbr2^−/−Tbx21^−/− mice are Tgfbr2^f/fTbx21^f/fdLck-cre mice. (A) Left: Pregated B cells to show GC B cells. Right: Pregated CD44⁺CD4⁺ T cells to show T_FH cells. (B) Pregated CD44⁺CD8⁺ T cells to show CD8⁺ T reg cells. (C) Pregated CD8⁺ T reg cells to show CXCR5 expression. Representative results from three independent experiments are shown (n = 3 for each genotype).