Table 2.

Univariate and multivariate cox analyses in gliomas.

Factor	CGGA set					TCGA set
	No. of samples	Univariate		Multivariate		No. of samples	Univariate		Multivariate
		p value	HR	p value	HR		p value	HR	p value	HR
Age
Increasing years	325	< 0.0001	1.038	0.446	1.006	1047	< 0.0001	1.059	< 0.0001	1.026
WHO grade
Benign progress	325	< 0.0001	0.171	< 0.0001	0.22	1047	< 0.0001	0.138	< 0.0001	0.207
Histopathology
Astrocytoma	66	< 0.0001	0.31	0.537	0.859	169	< 0.0001	0.192	0.743	0.927
Oligoastrocytoma	67	< 0.0001	0.163	0.007	0.466	114	< 0.0001	0.121	0.01	0.511
Oligodendroglioma	39	< 0.0001	0.022	< 0.0001	0.068	174	< 0.0001	0.11	0	0.068
Glioblastoma	138	Ref.	Ref.	Ref.	Ref.	590	Ref.	Ref.	Ref.	Ref.
TCGA molecular classification
Classical	70	< 0.0001	2.839	0.802	1.08	105	0.106	0.788	0.015	0.688
Mesenchymal	65	< 0.0001	4.946	0.093	1.714	117	0.317	0.866	0.334	0.863
Neural	76	0.009	0.458	0.158	0.618	70	0.188	0.806	0.023	0.69
Proneural	99	Ref.	Ref.	Ref.	Ref.	73	Ref.	Ref.	Ref.	Ref.
IDH status
Wild-type versus mutation	310	< 0.0001	4.101	0.298	1.337	926	< 0.0001	6.56	0.007	1.737
PIEZO1 expression
Increasing expression	325	< 0.0001	1.128	0.988	1	1047	< 0.0001	1.627	0.076	1.027