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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Nat Rev Cardiol. 2020 Mar 30;17(8):457–473. doi: 10.1038/s41569-020-0359-y

Table 3 |.

scRNA-seq studies of pluripotent stem cell models

Cell type Differentiation cell type Species Pluripotent stem cell type scRNA-seq method Refs
Pluripotent stem cells Reprogramming of CD19+ pre-B cells to iPSCs Mouse iPSC reprogramming MARS-seq 146
Undifferentiated iPSCs Human iPSC 10× Genomics 3ʹ 147
Differentiated cells Cardiomyocytes Human iPSC 10× Genomics 3ʹ 104
Cardiomyocytes Human iPSC 10× Genomics 3ʹ 103
Endothelial cells Human ESC (KhES1) Smart-seq 148
Endothelial cells Human iPSC 10× Genomics 3ʹ 63
Endothelial cells Human ESC (H9 and RC11) 10× Genomics 3ʹ 106

ESC, embryonic stem cell; iPSC, induced pluripotent stem cell; MARS-seq, massively parallel single-cell RNA-sequencing; scRNA-seq, single-cell RNA sequencing; Smart-seq, switching mechanism at the 5′ end of the RNA template sequencing.