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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Fertil Steril. 2016 Aug 25;106(4):795–819. doi: 10.1016/j.fertnstert.2016.07.1099

FIGURE 2.

FIGURE 2

Integration of evidence of health effect. Visualization of integration of the evidence of a health effect based on each articles finding and the level of evidence and confidence ratings for endpoints (A) Preterm Birth, (B) Miscarriage, (C) Stillbirth, (D) Low Birth Weight, (E) Birth Defects, (F) Sex Ratio, (G) Semen Quality and Fertility, (H) Paternal Birth Outcomes, (I) Prostate Cancer, (J) Testicular Cancer, (K) Female Reproductive Tract Cancers, and (L) Breast Cancer. The total number of articles for each endpoint is indicated below each chart. Evidence was integrated for each endpoint based on each article’s level of evidence and level of confidence. High, moderate, and low level of confidence findings were weighted by multiplying the number of articles by 3 for high, 2 for moderate, and 1 for low for all studies except where noted. *Four studies were not independent of each other and integration of evidence was adjusted (Materials and Methods). ↑ Indicates increased risk. ↓ Indicates decreased risk. **Two studies analyzed the same cohort, only the most recent study was included (Materials and Methods).